Onconephrology is the intersection of cancer and kidney care in patients with malignancies. It is a new subspecialty within nephrology that gained popularity over the past few years due to the vast innovations in cancer therapies and increased number of cancer survivors. New advances such as immune checkpoint inhibitors, chimeric antigen receptor T cells, and stem cell transplantation, may lead to complex kidney injuries involving acid-base balance, electrolyte disarray, and glomerular disorders.
We sought to demystify some of the associations between new cancer therapies and kidney function decline through a comprehensive database of onconephrotoxins, the Onconephrotoxin Library Collaboration (OLIC). Due to the nature of this ever-growing, fast-paced field, our efforts are never complete and they'll always be a "work-in-progress."
To find an onconephrotoxin, simply use the search field above, or browse through our database here.