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PARTNERS WITH
Alectinib
ALK (Anaplastic Lymphoma Kinase) inhibitor
MECHANISM OF ACTION
MECHANISM OF KIDNEY INJURY
Potential direct tubular injury
CLINICAL KIDNEY SYNDROME
Acute Kidney Injury
CARDIOVASCULAR ADVERSE EFFECTS
LYTE ABNORMALITIES
Elevation in serum Creatinine.
RISK FACTORS
MITIGATION STRATEGIES
SUGGESTIONS
NOTES/COMMENTS
PHARMACOKINETICS
Molecular Weight
Volume of Distribution
Plasma Protein Binding
Metabolism
Bioavailability
Half-life elimination
Time to peak
Excretion
Dialyzable?
REF:
PATHOLOGY SLIDES:
ENTRY UPDATES:
Mohamed Ibrahim
USA
Nov 7, 2024
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